China Endorses Avigan / Favipiravir For COVID-19 Disease Treatment

China Endorses Avigan / Favipiravir For COVID-19 Disease Treatment

Avigan Favipiravir (T-705) is a broad-spectrum inhibitor of viral RNA polymerase

China's health leadership announced they have found the Japanese-developed anti-influenza drug Avigan to be effective in treating COVID-19 disease patients.

Zhang Xinmin, China’s director of the National Center for Biotechnology Development said Avigan (Favipiravir) was found to be effective in 2 clinical trials completed in Wuhan and Shenzhen and involved 240 patients and 80 patients respectively.

During a conference in Beijing on March 17, 2020, Zhang said the medicine worked for coronavirus-related symptoms including pneumonia and had no obvious side effects.

Zhang said those who were given Avigan reported positive results after 4 days of therapy. This contrasts with a median of 11 days for those without the medication.

Zhang said more than 80 COVID-19 patients have participated in the clinical trial in The Third People's Hospital of Shenzhen, including 35 patients taking Favipiravir and 45 patients on a control group.

One of these clinical trials also found that X-rays confirmed improvements in lung conditions in about 91 percent of the patients who were given the medicine.

The director said he formally recommended the use of this medicine as a way to treat the COVID-19 disease, which is caused by the SARS-CoV-2 virus.

According to Zhang, a Chinese pharmaceutical company has been approved by the National Medical Products Administration to mass-produce the medication and ensure a stable supply.

The Avigan tablet was developed by the Fujifilm Group company, Toyama Chemical Co., Ltd., and is not distributed in the Japanese marketplace.